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產品應用

上海奧爾科特生物科技有限公司是研發、設計、制造科學實驗儀器與系統設備的專業企業,自1992年起致力于研發和生產生命科學實驗系統與設備,產品廣泛應用,為祖國的科學研究事業做出了貢獻。
奧爾科特公司產品為中國科學院、中國醫學科學院、軍事醫學科學院、北京大學、清華大學、復旦大學、上海交通大學、香港大學、阿斯利康、藥明康德等院校與企業采用。
奧爾科特公司產品被選用在國家高新技術研究發展項目、國家973計劃項目、國家863計劃項目、國家與軍隊重大計劃項目等各種重要科學研究,涵蓋醫學、藥物研發、化學、物理、生物、運動、心理、工業等領域。

在實驗研究中使用奧爾科特的產品,近年發表的部分科學研究論著
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Glutathione supplementation attenuates oxidative stress and improves vascular hyporesponsiveness in experimental obstructive jaundice. Oxidative Medicine & Cellular Longevity, 2015 , 2015 (11) :486148
Rosuvastatin attenuates atrial structural remodelling in rats with myocardial infarction through the Inhibition of the p38 MAPK signalling pathway. Heart Lung & Circulation, 2015 , 24 (4) :386-394
Dexmedetomidine directly increases tau phosphorylation. Journal of Alzheimers Disease Jad, 2015 , 44 (3) :839-50
Role of mitochondrial ATP-sensitive potassium channel-mediated PKC-ε in delayed protection against myocardial ischemia/reperfusion injury in isolated hearts of sevoflurane-preconditioned rats. Braz J Med Biol Res 48(6) 2015
Castration impairs erectile organ structure and function by inhibiting autophagy and promoting apoptosis of corpus cavernosum smooth muscle cells in rats. International Urology & Nephrology, 2015 , 47 (7) :1105
Heavy ethanol consumption aggravates the ischemic cerebral injury by inhibiting ALDH2 journal of stroke, 2015
Bauhinia championii flavone inhibits apoptosis and autophagy via the PI3K/Akt pathway in myocardial ischemia/reperfusion injury in rats. Drug Design Development & Therapy, 2015 , 9 :5933
Synthesis and pharmacological evaluation of a novel AT1 angiotensin II receptor antagonist with anti-hypertension and anti-tumor effects. Clinical & Experimental Hypertension, 2015, 37 (6) :490
Effect of GABA on blood pressure and blood dynamics of anesthetic rats. International journal of clinical Int J Clin Exp Med 2015;8(8):14296-14302
Effects of antiarrhythmic peptide 10 on acute ventricular arrhythmia. Asian Pacific Journal of Tropical Medicine, 2015 , 8 (3) :229-233
Establishment of a novel rat model of severe acute cholangitis. Iranian journal of basic medical sciences, 2015
Luteolin ameliorates hypertensive vascular remodeling through inhibiting the proliferation and migration of vascular smooth muscle cells. Evidence-Based Complementary and Alternative Medicine 2015
Exosomes derived from human umbilical cord mesenchymal stem cells relieve acute myocardial ischemic injury. Stem Cells International, 2015 , 2015 :761643
Trigeminal neuralgia increases cerebral blood flow in a focal cerebral ischemic model in rats. Int J Clin Exp Med. 2015; 8(4): 6544–6552.
Protection of granulocyte-colony stimulating factor to hemorrhagic brain injuries and its involved mechanisms: effects of vascular endothelial growth factor. Neuroscience.Volume 260, 28 February 2014, Pages 59-72
Resistance to rocuronium of rat diaphragm as compared with limb muscles. journal of surgical research, 2014
The role of aquaporin 4 in apoptosis after intracerebral hemorrhage. Journal of Neuroinflammation 2014
Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure. Journal of Biological Chemistry 2014
Dexmedetomidine renders a brain protection on hippocampal formation through inhibition of nNOS-NO signalling in endotoxin-induced shock rats. Brain injury, 2014
Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action. BMC pulmonary medicine, 2014
Protective effect of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats induced by yeast and potassium oxonate. Food and chemical toxicology, 2014
Naloxone postconditioning alleviates rat myocardial ischemia reperfusion injury by inhibiting JNK activity. Korean J Physiol Pharmacol. 2014 Feb;18(1):67-72
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis. PloS one, 2014
Deficiency of Smad3 results in enhanced inducible nitric oxide synthase–mediated hypotension in lipopolysaccharide-induced endotoxemia. Journal of Surgical Research Volume 187, Issue 2, April 2014, Pages 640-645
Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. European Journal of Pharmacology Volume 728, 5 April 2014, Pages 67-76
Dysregulation of neurotrophic and inflammatory systems accompanied by decreased CREB signaling in ischemic rat retina. xperimental Eye Research Volume 125, August 2014, Pages 156-163
The changes of technetium-99m-labeled annexin-V in delayed anesthetic preconditioning during myocardial ischemia /reperfusion. Molecular Biology Reports 2014
Protective effects of aliskiren on atrial ionic remodeling in a canine model of rapid atrial pacing . drugs and therapy, 2014
Ischemia/reperfusion-induced CHOP expression promotes apoptosis and impairs renal function recovery: the role of acidosis and GPR4. PloS one, 2014
Mechanism of the protective effect of Yulangsan flavonoid on myocardial ischemia/reperfusion injury in rats. Cellular Physiology and biochemistry 2014
Physiological disturbance may contribute to neurodegeneration induced by isoflurane or sevoflurane in 14 day old rats. PloS one, 2014

 

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